Short description: The 3-OMG test is a method used to measure glucose absorption in the small intestine. It is a reliable and accurate method for assessing glucose absorption in critically ill patients. The test involves measuring the serum concentration of 3-OMG, a monosaccharide that is absorbed from the small intestine via the same transporters as glucose but is not metabolized. The measurement of serum 3-OMG concentrations provides an accurate measure of glucose absorption. The test is used to determine the effectiveness of interventions aimed at improving glucose absorption in critically ill patients, such as the use of erythromycin.
References: [1, 2]
1. Deane AM, Wong GL, Horowitz M, Zaknic AV, Summers MJ, Di Bartolomeo AE, Sim JA, Maddox AF, Bellon MS, Rayner CK et al: Randomized double-blind crossover study to determine the effects of erythromycin on small intestinal nutrient absorption and transit in the critically ill. Am J Clin Nutr 2012, 95(6):1396-1402.
2. Gassel RJJ, Poll MCG, Schaap FG, Plummer M, Deane A, Olde Damink SWM: Postprandial rise of essential amino acids is impaired during critical illness and unrelated to small‐intestinal function. Journal of Parenteral and Enteral Nutrition 2022, 46(1):114-122.