I-BABP (intestinal bile acid-binding protein) is a protein found in enterocytes that is released into the bloodstream upon damage to the enterocyte membrane. I-BABP levels in the blood have been proposed as a biomarker for enterocyte damage and gastrointestinal dysfunction in critically ill patients. A study in critical care patients found a significant association between I-BABP levels and delayed gastric emptying
References:
Grootjans J, Thuijls G, Verdam F, Derikx JP, Lenaerts K, Buurman WA. Non-invasive assessment of barrier integrity and function of the human gut. World J Gastrointest Surg 2010 Mar 27;2(3):61e9.
Greis C, Rasuly Z, Janosi RA, Kordelas L, Beelen DW, Liebregts T. Intestinal T lymphocyte homing is associated with gastric emptying and epithelial barrier function in critically ill: a prospective observational study. Crit Care 2017 Mar 22;21(1):70