ICG PDR stands for indocyanine green plasma disappearance rate, which is a measure of liver function and splanchnic perfusion. ICG is a dye that is injected into the bloodstream and taken up by the liver, where it is metabolized and excreted into the bile. By measuring the rate at which ICG disappears from the plasma, clinicians can estimate the rate of liver function and blood flow to the splanchnic organs. ICG PDR can be measured either by serial blood samples or continuously by a transcutaneous pulse dye densitometer. Normal values of ICG PDR are over 18% per minute, and ICG has been shown to be a valuable method for dynamic assessment of liver function and as a prognostic tool in critically ill patients and those with acute liver failure. However, its role in the detection of splanchnic hypoperfusion is unclear and subject to several limitations, including dependence on hepatic uptake and excretion.
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