kasparbachmann – COSMOGI

19 October 2023Nutrient absorption, Nutrient digestion

Use of peptide based formula for enteral nutrition

Description: Enteral nutrition is usually provided using a whole protein formula. Peptide based formulas contain proteins that have been enzymatically hydrolysed to dipeptides and tripeptides. These hydrolysed proteins are often combined with a higher medium-chain triglyceride content to produce a […]

19 October 2023GI Motility - upper (oesophagus and stomach)

Body surface gastric mapping

Gastric Alimetry body surface gastric mapping (BSGM) is a non-invasive diagnostic test that measures gastric motility [1]. BSGM uses a stretchable high-resolution array of electrodes, a wearable reader, and a validated symptom-logging app to evaluate gastric function 12. BSGM offers […]

15 August 2023Nutrient digestion

Use of Parenteral Nutrition due to intolerance of EN

Parenteral Nutrition (PN) may be used to achieve caloric and micro-/macronutrient goals when enteral nutrition (EN) is not tolerated or contraindicated [1]. Depending on the relative proportion of both feeding routes on total delivery of medical nutrition therapy (MNT), PN […]

15 August 2023Nutrient digestion

Gastric pH

Gastric pH monitoring is a technique that measures the acidity of the stomach contents using a probe inserted through the nose or mouth into the stomach. Gastric pH monitoring can be used for diagnostic purposes in critically ill patients with […]

15 August 2023Nutrient digestion

Fecal Elastase 1

Faecal elastase 1 is a pancreatic enzyme that is excreted in the faeces and can be used as a marker of pancreatic function. Low levels of faecal elastase 1 can indicate pancreatic insufficiency, which can lead to malabsorption and other […]

15 August 2023Nutrient digestion

Composition of microbiome

Microbiome represents all microorganisms residing on the host (i.e., mouth, lungs, gut, skin) although the majority of bacterial species reside within the gut lumen. The gut microbiome is essential for the development of the gastrointestinal (GI) mucosal immune system, the […]

15 August 2023Nutrient absorption

Refractometry

Refractometry allows to identify the nature of gastric contents and thus allows to separate between gastric secretions and undigested food [1]. In case of delayed gastric emptying, the refractive index is higher [1]. Feasibility/Equipment: Refractometry requires training of personnel, but […]

15 August 2023Nutrient absorption

I-BABP

I-BABP (intestinal bile acid-binding protein) is a protein found in enterocytes that is released into the bloodstream upon damage to the enterocyte membrane. I-BABP levels in the blood have been proposed as a biomarker for enterocyte damage and gastrointestinal dysfunction […]

15 August 2023Nutrient absorption

FGF-19

FGF-19 is secreted from the intestinal epithelial cells in response to bile acids released to the intestinal lumen upon feeding. FGF-19 promotes glucose uptake in adipocytes and has a role in bile acid homeostasis and hepatic protein metabolism. FGF-19 levels […]

15 August 2023Nutrient absorption

Citrulline

Citrulline is an amino acid which forms a key intermediate in the urea cycle. It is also produced as a by-product of the enzymatic production of nitric oxide from arginine and in the gastrointestinal tract from glutamine. Citrulline has been […]